Cen-ComMed

Drug Discovery Working Group

The “Drug Discovery Working Group” is a research group focused on advancing the field of drug discovery. This research group comprises a multidisciplinary team of scientists, pharmacologists, biochemists, and medical doctors collaborating to identify and develop novel therapeutic agents to address unmet medical needs. This working group utilized cutting-edge technology to push the boundaries of science to discover innovative drugs that improve patient outcomes and quality of life. Through rigorous research, strategic collaborations, and technological innovation, this research group is committed to making significant contributions to the field of drug discovery.

List of Projects:

  1. HERBMed (Herbal Exploration and Research for Biological application in Medicine)

The HERBMed project is an ambitious research initiative with a focus on exploring the potential of herbal medicine to enhance patient care. This project rigorously investigates therapeutic properties of medicinal plants to discover new treatments that are safe, effective and accessible.

 

  • The Use of Traditional Herbal Medicines, Bioactive Metabolites and Immune-Related Behavior in Rural Communities in Indonesia-Malaysia.

(ongoing)

Chief Investigator: Rudiansyah Harahap

  • Identification and Evaluation of Antidiabetic Activity in Extracts of Melatonin from Zingiber Officinale Rosc.

(ongoing)

Chief Investigator: Nabil Hajar

  • Effectivity of Clitoria ternatea for Cellular Damage Repair of Hepatocytes in White Wistar Rats (Rattus Norvegicus) with Toxic Hepatitis.

(ongoing)

Chief Investigator: Devita Diatri

  • Development of an Autolysis Cream with an Active Compound of Protease Enzymes from Sea Bacteria for Wound Healing.

(ongoing)

Chief Investigator: Maya Dian Rakhmawatie

  • The Effect of Cream made from Clitoria ternatea L Extract on Amount of Fibroblast Male Wistar Rat (Rattus norvegicus) Exposed to UV-B

(completed)

Published:

Purnamasari et.al., CLITORIA TERNATEA CREAM FLOWERS EXTRACT INCREASE SKIN FIBROBLAS FROM ULTRAVIOLET B-INDUCED PHOTOAGING, Eur. Chem. Bull. 2023, 12 (6), 2654 – 2661

Chief Investigator: Rina Purnamasari

  • Melatonin: Expression Analysis of Regulator, Coding, and Transporter Genes as a Predictor Factor for Diabetes Mellitus Type-2 in the Javanese Population.

(completed)

Published:

Tursinawati Y, Kartikadewi A, Yuniastuti A, et al. Overexpression of miR-29b in Plasma of Javanese Type 2 Diabetes Mellitus Patients in Semarang, Indonesia. Turkish J Endocrinol Metab 2022; 26: 208–212.

https://www.researchgate.net/publication/365985581_Overexpression_of_miR-29b_in_Plasma_of_Javanese_Type_2_Diabetes_Mellitus_Patients_in_Semarang_Indonesia

Chief Investigator: Yanuarita Tursinawati

  1. MicroX

The MicroX project is a research initiative focused on enhancing our understanding of microorganisms and their role in health and disease. This project aims to unlock the vast potential of microorganisms and its application in evidence-based medicine to tackle global challenges such as anti-microbial resistance and environmental degradation.

  • Antibacterial Activity and Secondary Metabolite Profiles of Bacillus sp.

(ongoing)

Chief Investigator: Maya Dian Rakhmawatie

  • Evaluating the Antithrombotic Potential of Protease Bacillus cereus HSFI-10 and Bacillus thuringiensis HSFI-12 on Rattus Model.

(ongoing)

Chief Investigator: Maya Dian Rakhmawatie

  • Main Component Analysis of Liquid Chromatography-Mass Spectoscopy (LC-MS) Secondary Metabolites Streptomyces parvus InaCC A758 Co-Culture Results.

(ongoing)

Chief Investigator: Maya Dian Rakhmawatie

  • Optimalization of Fermentation and Co-Culture of Indonesian Actinomycetes for Producing Novel Antimycobacterium.

(ongoing)

Chief Investigator: Maya Dian Rakhmawatie

Chief Investigator

Rudiansyah Harahap

Nabil Hajar

Devita Diatri

Maya Dian Rakhmawatie

Rina Purnamasari

Yanuarita Tursinawati